Indians outfielder David Murphy and designated hitter/outfielder Nick Swisher were placed on the 15-day disabled list Sunday morning.
Murphy is bothered by a right abdominal strain he aggravated in Saturday's victory over the New York Yankees at Yankee Stadium. Swisher has been bothered by right knee soreness.
Murphy will undergo an MRI in Cleveland Monday morning.
"From a baseball standpoint, this is a tough area," Murphy said before the moves were announced. "Off the top of my head, I don't know that this is something that would bother me for 15 days, it doesn't necessarily feel like it would, but I don't feel like I'm going to be able to play for a few, at least. I know a move has been discussed. I'm understanding of whatever happens because I know we've got some other guys banged up and every spot on the roster is very important.
"It's always bad timing. It's unfortunate."
Swisher said he needed to get healthy.
"It's time to take a break," Swisher said. "We've just got to get healthy. It's been a very frustrating year, we've battled through a lot of pain this year and it's affected a lot of things. It's to the point now where it physically shows all the time.
"We need to figure out what's going on because this is something that's been banging around for a while."
The Tribe called up infielder Zach Walters and outfielder Tyler Holt from Triple-A Columbus. Walters was acquired in a July 31 trade with the Washington Nationals for shortstop Asdrubal Cabrera.
Walters is in the lineup in today's finale of a three-game series against the New York Yankees in Yankee Stadium. Walters is playing left field and batting seventh.
Walters has hit .310 in 67 minor league games this season with 17 homers and 56 RBI. He was a ninth-round draft pick of the Arizona Diamondbacks in 2010 out of the University of San Diego.
This is Holt's third stint with the Indians. Holt was hitting .311 in 58 minor league games with two homers and 15 RBI. Holt was optioned to Columbus on Tuesday. He leads the Indians' farm system with 31 stolen bases.