INTERLEAGUE: Brewers 4, Red Sox 0
Yovani Gallardo made his second straight scoreless start and the Milwaukee Brewers completed a three-game sweep of the host Boston Red Sox with a victory Sunday.
The World Series champion Red Sox, who never had a losing record last year, fell to 2-4 and matched their longest skid of 2013.
AMERICAN LEAGUE: Yankees 6, Blue Jays 4
CC Sabathia pitched six innings for his first victory of the season, Brett Gardner hit a two-run home run and the New York Yankees beat the host Toronto Blue Jays.
Sabathia (1-1) allowed four runs and seven hits, walked none and struck out six.
Orioles 3, Tigers 1
Chris Tillman outpitched Justin Verlander, allowing one run while working into the ninth and the Baltimore Orioles beat the host Detroit Tigers to avoid getting swept.
Tillman (1-0) gave up five hits, including Torii Hunter’s solo homer in the fourth, in 8⅓ innings.
Rangers 3, Rays 0
Yu Darvish allowed seven hits over seven innings in his season debut, Elvis Andrus hit a two-run homer, and the visiting Texas Rangers avoided a three-game sweep by beating the Tampa Bay Rays.
Darvish (1-0) struck out six and walked one.
White Sox 5, Royals 1
Chris Sale gave up four singles in eight scoreless innings as the Chicago White Sox defeated the host Kansas City Royals.
Alexei Ramirez and Tyler Flowers each drove in two runs as the White Sox won the series finale after dropping the first two games.
Astros 7, Angels 4
Scott Feldman threw seven strong innings, five Astros homered, and Houston snapped a three-game losing streak with a victory over the visiting Los Angeles Angels.
Feldman (2-0) did not allow a hit until two outs in the fourth, when Josh Hamilton dribbled one toward first base that went under the glove of Feldman, who charged at it off the mound.
Athletics 6, Mariners 3
Reigning AL saves leader Jim Johnson struck out two and closed it out this time after losing back-to-back outings to begin with his new team, sealing the host Oakland Athletics’ victory over the Seattle Mariners.
NATIONAL LEAGUE: Reds 2, Mets 1
Alfredo Simon pitched seven impressive innings in his first start in more than two years and began the go-ahead rally with his second career hit, helping the Cincinnati Reds beat the host New York Mets to salvage a win in the three-game series.
Padres 4, Marlins 2
Pinch-hitter Alexi Amarista celebrated his 25th birthday by delivering a go-ahead, three-run homer in the seventh inning to lift the San Diego Padres to a victory over the host Miami Marlins.
Ian Kennedy (1-1) allowed one run and three hits in six innings for the Padres.
Nationals 2, Braves 1
Ian Desmond led off the seventh inning with a home run — the only run of the game scored on a hit — and the host Washington Nationals and their makeshift lineup avoided a sweep with a win over the Atlanta Braves.
Pirates 2, Cardinals 1
Tony Sanchez hit a tiebreaking RBI double in the seventh inning and the host Pittsburgh Pirates edged the St. Louis Cardinals.
Sanchez’s double to deep center field with two outs snapped a 1-1 tie.
Cubs 8, Phillies 3
Ryan Kalish hit a two-run double and an RBI triple and the host Chicago Cubs beat the Philadelphia Phillies to avoid a sweep.
Diamondbacks 5, Rockies 3
Mark Trumbo homered for the fourth straight game, and the visiting Arizona Diamondbacks averted a sweep by beating Colorado.