BEREA: Browns rookie defensive end Myles Garrett faces an uphill battle in receiving the green light to play Sunday at home against the Cincinnati Bengals.

On Friday, the Browns listed Garrett as questionable to make his NFL regular-season debut this weekend, but the organization will likely err on the side of caution with the No. 1 overall pick in this year’s draft who practiced Thursday for the first time since he suffered a high-ankle sprain Sept. 6 when a teammate fell on his right leg.

Garrett has sat out the first three games, and the Browns (0-3) are leaning toward keeping him idle against the Bengals (0-3). If he continues to rest this weekend as expected, he would be in line to return Oct. 8 at home against the New York Jets. Carl Nassib has started all three games in Garrett’s absence.

“Myles will get snaps when he’s healthy,” defensive coordinator Gregg Williams said Friday. “... When he’s ready to cut it loose and there’s no setbacks, he’ll be fine, and we’ll use him in lots of different ways.”

The Browns also ruled out starting strongside linebacker Jamie Collins (concussion) for the second consecutive game and listed starting defensive tackle Danny Shelton (calf), wide receiver Sammie Coates (hamstring) and tight end Randall Telfer (knee) as questionable.

Garrett is not only trying to come back from an ankle injury that typically requires four to six weeks of recovery, but he’s also fighting a cold this week. Garrett has insisted he doesn’t want to rush his return. He conceded Thursday playing this weekend “might be” considered rushing his comeback.

Garrett participated in team drills Thursday, coach Hue Jackson said, but he was listed as a limited participant on the injury report Thursday and Friday. Jackson and the team’s medical personnel will make a final decision about whether Garrett plays.

“He moved around well [Thursday], did some things [Friday] and we’re going to huddle with the medical team and the football staff and see what’s best,” Jackson said.

Garrett said watching the Browns go winless through three weeks has been “a horrible feeling” of “helplessness,” and he’s eager to assist them as soon as possible.

On the other hand, Garrett also knows the downside of returning too quickly from a high-ankle sprain. The one he suffered last season to his left leg forced him to miss two games at Texas A&M, but he pushed through the injury during the second half of the season and experienced a drop in production. He finished with 8.5 sacks last season as a junior after racking up 12.5 as a sophomore and 11.5 as a freshman.

“He’s been working so hard behind the scenes and hasn’t missed a meeting,” Williams said. “He has the respect of everybody in the locker room, the training room, the strength department, the coaching, all that stuff, so we’ll see as he takes steps and see how his body handles it.”

As for Shelton, he suffered a calf injury during Wednesday’s practice and had an MRI on Thursday. Jackson said the test provided “good news,” so Shelton is not expected to be out long term, although his status for Sunday remains unclear. Shelton didn’t practice Friday.

If Shelton is sidelined against the Bengals, the Browns will rely on backups Jamie Meder, Larry Ogunjobi and Caleb Brantley more than they normally would.

“It’s the name of the game,” said Ogunjobi, a rookie third-round pick. “If my opportunity presents itself, I’ll be ready to make the most of it.”

James Burgess is expected to start in place of Collins for the second week in a row.

“Burgess played very well,” Williams said. “He was very attacking.”

Nate Ulrich can be reached at nulrich@thebeaconjournal.com. Read the Browns blog at www.ohio.com/browns. Follow him on Twitter at www.twitter.com/NateUlrichABJ and on Facebook www.facebook.com/abj.sports.