Munchie Legaux hit Damon Julian for a 39-yard touchdown pass with 13 seconds to play, and Cincinnati beat host Virginia Tech at FedEx Field.
Trailing by four after a Hokies touchdown, the Bearcats (3-0) took over at their own 15 with 1:43 to play and moved downfield in nine plays for the score, capping a seesaw fourth quarter that brought to life a sleepy game.
Legaux completed 19-of-42 passes for a career-high 376 yards with three touchdowns and one interception. Kenbrell Thompkins also set career highs for Cincinnati with seven catches for 134 yards and a score.
Logan Thomas was 17-for-30 for 242 yards with one touchdown and two interceptions for the Hokies (3-2), who have lost two games to unranked Big East schools in one of the most trying Septembers in recent history under coach Frank Beamer.
— Associated Press