Three-time All-Star Grady Sizemore might get another chance in the big leagues.

Sizemore, 38, who signed a minor-league deal this week with the Philadelphia Phillies, is expected to be called up soon from Triple-A Lehigh Valley.

The Phillies are losing patience with Domonic Brown, 26, who hit 23 homers in the first half last year, played in the All-Star Game and was once considered an untouchable prospect.

Brown is struggling this year. He’s batting .218 with five homers and 38 RBI. He has only 17 extra-base hits and his slugging percentage (.321) is seventh worst in the major leagues.

“Well, Domonic is our left fielder as we speak,” manager Ryne Sandberg said. Not exactly a ringing endorsement.

Sandberg held Brown out of the starting lineup Friday for the second straight night.

“It’s just been a frustrating year for myself,” Brown said. “I mean, we still have three months to go, but I have to pick it up for sure.”

Sizemore began the year as Boston’s starting center fielder after missing the last two years following various injuries. He batted .216 with 10 doubles, two triples, two homers and 15 RBI for the Red Sox before he was released June 18.

Sizemore was an All-Star with the Indians from 2006-08 and won two Gold Gloves in 2007-08. He’s a career .266 hitter with 141 homers, 473 RBI and 139 stolen bases.

“I’d like to have more production in the outfield,” Phillies General Manager Ruben Amaro Jr. said. “It’s pretty simple. If we think after watching him play in Lehigh Valley he can help, then we’ll bring him.”

PITCHERS TRADED —The Los Angeles Angels acquired veteran Jason Grilli from the Pittsburgh Pirates for fellow reliever Ernesto Frieri in an attempt to solidify the bullpen. Grilli, 37, has struggled with his command this season, and was 0-2 with a 4.87 ERA and 11 saves in 22 appearances. He was pivotal to the Pirates’ resurgence last year, when he piled up 33 saves and had a 2.70 ERA in helping the club to a 94-68 record. Grilli is expected to join the Angels in Kansas City today. Frieri, 28, had a career-best 37 saves for Los Angeles last year, but the right-hander is just 0-3 with 6.39 ERA and 11 saves in 34 appearances this season.

CATCHER GROGGY — The Philadelphia Phillies placed catcher Carlos Ruiz on the seven-day disabled list with concussion-like symptoms a day after he was hit in the head by a pitch from Miami’s A.J. Ramos in the 11th inning of a 14-inning victory Thursday. Ruiz stayed in the game, running the bases in the 11th, and caught three more innings. He is batting .257 with two homers and 14 RBI in 66 games this season. To replace Ruiz, the Phillies called up catcher Koyie Hill from Triple-A Lehigh Valley and designated outfielder Zach Collier for assignment.

DRUG SUSPENSIONS — Seattle Mariners minor-league outfielders Jamal Austin and Jabari Blash were suspended 50 games each after second positive tests for a “drug of abuse.” Austin is with the Double-A Jackson Generals of the Southern League, and Blash is on the roster of the Triple-A Tacoma Rainiers of the Pacific Coast League.

AROUND THE BASES — The Minnesota Twins put shortstop/center fielder Danny Santana on the 15-day disabled list with a deep bone bruise to the left knee, and recalled right-hander Yohan Pino from Triple-A Rochester. ... The Baltimore Orioles put right-hander Bud Norris on the 15-day disabled list with a strained right groin, and recalled reliever Evan Meek from Triple-A Norfolk. ... The Arizona Diamondbacks promoted infielder/outfielder Nick Evans from Reno and optioned right-hander Zeke Spruill to the Triple-A club. ... New York Mets third baseman David Wright was scratched from the lineup night against the Pittsburgh Pirates because of a sore left shoulder.