Marcus Mariota threw a touchdown pass and ran for two additional scores and the No. 3 Oregon Ducks made easy work of lower-tier Nicholls with a home victory in the season opener.
Mariota, who set an Oregon record with 38 touchdowns last season as a redshirt freshman, completed 12 of 21 passes for 234 yards before sitting after the third quarter when the Ducks had built a 45-3 lead.
Mariota also ran for 113 yards for his second career game with more than 100 yards rushing.
De’Anthony Thomas ran for 128 yards and two more touchdowns for Oregon in the debut of new coach Mark Helfrich.
Oregon totaled 772 yards total, including an amazing 500 of them on the ground.
The Ducks scored 66 points despite having the ball for fewer than 20 minutes of the game clock (19:46).
— Associated Press