Stephen Wilson

LONDON: Seven-time champion Roger Federer was stunned by 116th-ranked Sergiy Stakhovsky in the second round of Wimbledon on Wednesday, his earliest loss in a Grand Slam tournament in 10 years.

The 27-year-old Ukrainian outplayed Federer on Centre Court, serving and volleying his way to a 6-7 (5), 7-6 (5), 7-5, 7-6 (5) victory that stands out as one of the biggest upsets in Grand Slam history.

“Magic,” Stakhovsky said. “I couldn’t play any better today.”

The result capped a chaotic day at Wimbledon when seven players were forced out by injuries, and former champion Maria Sharapova fell in the second round to a qualifier.

Federer’s loss ended his record streak of reaching at least the quarterfinals at 36 consecutive Grand Slam tournaments, a run that began at Wimbledon in 2004, shortly after a third-round exit at that year’s French Open.

The owner of a record 17 major championships, Federer hadn’t been beaten in the second round or earlier since a first-round defeat at the 2003 French Open.

Federer’s shocking defeat was his earliest at the All England Club since a first-round loss in 2002 to No. 154-ranked Mario Ancic. Stakhovsky is the lowest-ranked player to beat Federer at any event since then.

“I’m still in disbelief,” Stakhovsky said. “When you play Roger Federer at Wimbledon it’s like you are playing two persons. First you play Roger Federer, then you play his ego, and on the Centre Court of Wimbledon, where he is historical. So that’s like playing two against one.”

The third-seeded Sharapova was knocked out by a 131st-ranked qualifier. The 2004 Wimbledon champion was beaten 6-3, 6-4 by Michelle Larcher de Brito of Portugal in the second round.

Sharapova slipped and fell several times on the grass on Court 2 and received medical treatment from the trainer in the second set.

It wasn’t serious enough to force Sharapova to quit, as so many others did.

Among the casualties: second-seeded Victoria Azarenka (walkover, right knee), men’s No. 6 Jo-Wilfried Tsonga (retirement, left knee), John Isner (retirement, left knee) and Steve Darcis (walkover, right shoulder). Darcis was the man who stunned two-time champion Rafael Nadal in the first round Monday.

Also out: 10th-seeded Marin Cilic (walkover, left knee); 2006 quarterfinalist Radek Stepanek (retirement, left hamstring); and Yaroslava Shvedova (walkover, right arm).

The International Tennis Federation said the seven players forced out is believed to be the most in one day at any Grand Slam event in the 45 years of the Open era.

If that wasn’t enough, the tournament lost five former No. 1 players Wednesday: Sharapova, Azarenka, Caroline Wozniacki and Ana Ivanovic among the women, and Lleyton Hewitt among the men.

With Azarenka and Sharapova gone, the prospect of Serena Williams lifting the women’s trophy for a sixth time look even stronger. Williams, who is riding a 32-match winning streak, had already been considered the overwhelming title favorite.

There were a few moments of normality on this crazy day at the All England Club.

Second-seeded Andy Murray advanced easily to the third round with a 6-3, 6-3, 7-5 victory over Yen-hsun Lu of Taiwan on Court 1.

The 20-year-old Larcher de Brito played the match of her life against Sharapova on Court 2 to reach the third round of a Grand Slam for only the second time.

Larcher de Brito held her nerve in the final 10-minute, 18-point game to serve out the match. She saved two break points and finally converted on her fifth match point when Sharapova hit a forehand into the net.

“I can’t believe it,” Larcher de Brito said. “I just tried to stay calm. I just played so well. I just hung in there. In the last couple of points or games I just gave it my all and went for it.”

Azarenka, the two-time Australian Open champion, pulled out after hurting her right knee in her opening-round win against Maria Joao Koehler.

She withdrew minutes before her second-round match against Flavia Pennetta.

Murray’s victory came not long after his potential quarterfinal opponent, Tsonga, retired with a left knee injury while trailing Ernests Gulbis 3-6, 6-3, 6-3.

The tournament also lost 2002 champion Hewitt, who was ousted by 189th-ranked German qualifier Dustin Brown, 6-4, 6-4, 6-7 (3), 6-2.

Ninth-seeded Wozniacki slumped to a 6-2, 6-2 loss to 196th-ranked Czech qualifier Petra Cetkovska, continuing her disappointing run since finishing 2011 as No. 1.